Nervisign 300 mg Capsules contain pregabalin, a medicine belonging to the gabapentinoid class. Pregabalin acts on the nervous system by influencing the transmission of nerve signals.
Pregabalin is prescribed for certain neurological conditions, including neuropathic (nerve) pain. Depending on the approved product information and the patient’s clinical circumstances, pregabalin may also be prescribed for partial-onset seizures alongside other medicines and generalised anxiety disorder in adults.
Unlike conventional painkillers, pregabalin works by affecting nerve signalling rather than directly treating inflammation or providing general pain relief.
What Is Pregabalin 300 mg Used For?
Pregabalin may be prescribed by a healthcare professional for:
1. Neuropathic Pain
Neuropathic pain develops when nerves are damaged or do not function properly. It can cause burning, shooting, stabbing or electric-shock-like sensations, as well as tingling and numbness.
2. Peripheral and Central Nerve Pain
Pregabalin may be prescribed for nerve pain associated with certain conditions, including diabetic nerve damage and pain following shingles.
3. Other Approved Medical Uses
Depending on the applicable product licence, pregabalin may also be prescribed for partial-onset epilepsy and generalised anxiety disorder in adults.
How Does Pregabalin Work?
Pregabalin binds to a specific subunit of voltage-gated calcium channels in the nervous system. This influences the release of certain neurotransmitters involved in nerve signalling.
In patients with neuropathic pain, this action can help reduce abnormal pain signalling.
Pregabalin is not an ordinary over-the-counter painkiller and should only be used for conditions assessed by a qualified healthcare professional.
Important Safety Information
Pregabalin 300 mg is a prescription medicine. The appropriate dose depends on the patient’s condition, kidney function, response to treatment and other medicines.
- Use only when prescribed by an authorised healthcare professional.
- Do not change the dose without medical advice.
- Do not share this medicine with another person.
- Do not stop taking pregabalin suddenly. Treatment generally needs to be reduced gradually under medical supervision.
- Pregabalin can cause dependence and withdrawal symptoms.
- Avoid alcohol unless your prescriber confirms it is safe.
- Do not drive or operate machinery if you experience dizziness, sleepiness or impaired concentration.
Pregabalin can also cause serious breathing difficulties, particularly when combined with opioids or other medicines that cause sedation. Seek urgent medical assistance if breathing becomes slow or difficult.
Possible Side Effects
Commonly reported side effects include:
- Dizziness
- Sleepiness or tiredness
- Headache
- Blurred vision
- Swelling in the hands or feet
- Weight gain
- Difficulty concentrating
Not everyone experiences side effects. Contact a healthcare professional if symptoms persist or become concerning. Seek emergency assistance for severe breathing difficulties or signs of a serious allergic reaction.
Storage Information
Store Nervisign capsules according to the instructions printed on the original packaging and accompanying patient information leaflet.
Keep medicines out of the reach and sight of children. Do not use capsules beyond their expiry date.
Frequently Asked Questions
1. What is Pregabalin 300mg used for?
Pregabalin 300mg is a capsule strength containing pregabalin. It may be prescribed for neuropathic pain and, depending on the product’s approved indications, certain seizure disorders and generalised anxiety disorder.
2. Is Pregabalin a painkiller?
Pregabalin is used to manage certain types of nerve pain. Unlike conventional painkillers such as paracetamol, it works by affecting nerve signalling.
3. What type of pain does Pregabalin treat?
It is prescribed for neuropathic pain, which can involve burning, shooting, stabbing, tingling or electric-shock-like sensations.
4. How long does Pregabalin take to work?
Some patients may notice improvement after a few weeks. The response varies depending on the individual and the condition being treated.
5. Is Pregabalin 300mg a high dose?
300mg is the amount of pregabalin in one capsule, not necessarily the patient’s daily dose. The appropriate daily dose is determined by a prescriber based on individual circumstances.
6. Can Pregabalin cause sleepiness?
Yes. Dizziness and sleepiness are common side effects. Patients should avoid driving if affected.
7. Can Pregabalin cause dependence?
Yes. Pregabalin can cause dependence, tolerance and addiction in some people. Stopping suddenly can cause withdrawal symptoms, so dose reduction should be medically supervised.
8. Can Pregabalin be taken with other painkillers?
Some medicines can interact with pregabalin, particularly opioids and other medicines that cause sedation. Always consult a doctor or pharmacist before combining treatments.
9. Can I stop taking Pregabalin suddenly?
No. Sudden discontinuation can cause withdrawal symptoms and may increase seizure risk in people taking it for epilepsy. A healthcare professional should guide any reduction.

